Relevante Publikationen

Literatur zu TENS

Overarching review

Paley CA, Wittkopf PG, Jones G, Johnson MI. Does TENS Reduce the Intensity of Acute and Chronic Pain? A Comprehensive Appraisal of the Characteristics and Outcomes of 169 Reviews and 49 Meta-Analyses. Medicina (Kaunas). 2021;57(10):1060.

Other systematic reviews and/or meta-analyses showing effectiveness of TENS therapy

Bjordal JM, Johnson MI, Lopes-Martins RA, Bogen B, Chow R, Ljunggren AE. Short-term efficacy of physical interventions in osteoarthritic knee pain. A systematic review and meta-analysis of randomised placebo-controlled trials. BMC Musculoskelet Disord. 2007;8:51.

Jauregui JJ, Cherian JJ, Gwam CU, et al. A Meta-Analysis of Transcutaneous Electrical Nerve Stimulation for Chronic Low Back Pain. Surg Technol Int. 2016;28:296-302

Osiri M, Welch V, Brosseau L, Shea B, McGowan JL, Tugwell P, Wells GA. Transcutaneous electrical nerve stimulation for knee osteoarthritis. Cochrane Database of Systematic Reviews 2000, Issue 4. Art. No.: CD002823.

Wu LC, Weng PW, Chen CH, Huang YY, Tsuang YH, Chiang CJ. Literature Review and Meta-Analysis of Transcutaneous Electrical Nerve Stimulation in Treating Chronic Back Pain. Reg Anesth Pain Med. 2018;43(4):425-433

Systematic reviews and/or meta-analyses not showing benefit of TENS therapy

Brosseau L, Milne S, Robinson V, et al. Efficacy of the transcutaneous electrical nerve stimulation for the treatment of chronic low back pain: a meta-analysis. Spine (Phila Pa 1976). 2002;27(6):596-603

Gibson W, Wand BM, Meads C, Catley MJ, O'Connell NE. Transcutaneous electrical nerve stimulation (TENS) for chronic pain - an overview of Cochrane Reviews. Cochrane Database Syst Rev. 2019 Apr 3;4(4):CD011890.

Khadilkar A, Odebiyi DO, Brosseau L, Wells GA. Transcutaneous electrical nerve stimulation (TENS) versus placebo for chronic low-back pain. Cochrane Database Syst Rev. 2008;2008(4):CD003008.

Kroeling P, Gross A, Graham N, et al. Electrotherapy for neck pain. Cochrane Database Syst Rev. 2013;(8):CD004251.

Milne S, Welch V, Brosseau L, et al. Transcutaneous electrical nerve stimulation (TENS) for chronic low back pain. Cochrane Database Syst Rev. 2001;(2):CD003008.

Rutjes_AWS, Nüesch_E, Sterchi_R, Kalichman_L, Hendriks_E, Osiri_M, Brosseau_L, Reichenbach_S, Jüni_P. Transcutaneous electrostimulation for osteoarthritis of the knee. Cochrane Database of Systematic Reviews 2009, Issue 4. Art. No.: CD002823.

Investigation of reasons for heterogenous outcomes

Bennett M.I. et al. Methodological quality in randomised controlled trials of transcutaneous electric nerve stimulation for pain: Low fidelity may explain negative findingsPain 152 (2011) 1226–1232

Pallett, EJ and Rentowl, P and Johnson, MI and Watson, PJ (2014) Implementation fidelity of self-administered transcutaneous electrical nerve stimulation (TENS) in patients with chronic back pain: an observational study. Clinical Journal of Pain, 30 (3): 224-231

Publications showing that treatment relies on its accurate and repeated application

Aarskog R, Johnson MI, Demmink JH, et al. Is mechanical pain threshold after transcutaneous electrical nerve stimulation (TENS) increased locally and unilaterally? A randomized placebo-controlled trial in healthy subjects. Physiother Res Int. 2007;12:251–263

Bjordal JM, Johnson MI, Ljunggreen AE. Transcutaneous electrical nerve stimulation (TENS) can reduce postoperative analgesic consumption: a meta-analysis with assessment of optimal treatment parameters for postoperative pain. Eur J Pain. 2003;7:181–188

Cheing GL, Luk ML. Transcutaneous electrical nerve stimulation for neuropathic pain. J Hand Surg Br. 2005;30:50–55.

Facci LM, Nowotny JP, Tormen F, Trevisani VFM. Effects of transcutaneous electrical nerve stimulation (TENS) and interferential currents (IFC) in patients with nonspecific chronic low back pain: randomized clinical trial. Sao Paulo Med J. 2011;129:206–216

Law PP, Cheing GL. Optimal stimulation frequency of transcutaneous electrical nerve stimulation on people with knee osteoarthritis. J Rehabil Med. 2004;36:220–225

Marchand S, Charest J, Li J, et al. Is TENS purely a placebo effect? A controlled study on chronic low back pain. Pain. 1993;54:99–106

Moran F, Leonard T, Hawthorne S, et al. Hypoalgesia in response to transcutaneous electrical nerve stimulation (TENS) depends on stimulation intensity. J Pain. 2011;12:929–935

Rakel B, Cooper N, Adams HJ, et al. A new transient sham TENS device allows for investigator blinding while delivering a true placebo treatment. J Pain. 2010;11:230–238.

Rakel B, Frantz R. Effectiveness of transcutaneous electrical nerve stimulation on postoperative pain with movement. J Pain. 2003;4:455–464

Literatur zu technikunterstützter Bewegungstherapie

(Therapie, die hinsichtlich des Aufwands, der bekannten positiven Wirkungen und der Adhärenz als einschränkender Faktor als ähnlich wie die TENS-Therapie angesehen wird - wird verwendet, um die Lücke zu schließen, dass keine klinischen Daten für den Einsatz der technologiegestützten TENS-Therapie verfügbar sind)

Systematic reviews and meta-analyses

Chen, T.; Or, C. K.; Chen, J. (2021): Effects of technology-supported exercise programs on the knee pain, physical function, and quality of life of individuals with knee osteoarthritis and/or chronic knee pain: A systematic review and meta-analysis of randomized controlled trials. In: Journal of the American Medical Informatics Association 28 (2), S. 414–423. DOI: 10.1093/jamia/ocaa282.

Jang, S.; Lee, B.; Lee, E.; Kim, J.; Lee, J. I.; Lim, J.-Y.; Hwang, J. H. (2023): A Systematic Review and Meta-Analysis of the Effects of Rehabilitation Using Digital Healthcare on Musculoskeletal Pain and Quality of Life. In: Journal of pain research 16, S. 1877–1894. DOI: 10.2147/JPR.S388757.

Thompson, D.; Rattu, S.; Tower, J.; Egerton, T.; Francis, J.; Merolli, M. (2023): Mobile app use to support therapeutic exercise for musculoskeletal pain conditions may help improve pain intensity and self-reported physical function: a systematic review. In: Journal of physiotherapy 69 (1), S. 23–34. DOI: 10.1016/j.jphys.2022.11.012.

Clinical studies

Abadiyan, F.; Hadadnezhad, M.; Khosrokiani, Z.; Letafatkar, A.; Akhshik, H. (2021): Adding a smartphone app to global postural re-education to improve neck pain, posture, quality of life, and endurance in people with nonspecific neck pain: a randomized controlled trial. In: Trials 22 (1). DOI: 10.1186/s13063-021-05214-8.

Almhdawi, K. A.; Obeidat, D. S.; Kanaan, S. F.; Oteir, A. O.; Mansour, Z. M.; Alrabbaei, H. (2020): Efficacy of an innovative smartphone application for office workers with chronic non-specific low back pain: a pilot randomized controlled trial. In: Clinical rehabilitation 34 (10), S. 1282–1291. DOI: 10.1177/0269215520937757.

Irmak, A.; Bumin, G.; Irmak, R. (2012): The effects of exercise reminder software program on office workers' perceived pain level, work performance and quality of life. In: Work (Reading, Mass.) 41 Suppl 1, S. 5692–5695. Online verfügbar unter

Irvine, A. B.; Russell, H.; Manocchia, M.; Mino, D. E.; Cox Glassen, T.; Morgan, R. et al. (2015): Mobile-Web app to self-manage low back pain: randomized controlled trial. In: Journal of Medical Internet Research 17 (1), e1. DOI: 10.2196/jmir.3130.

Lee, J.; Lee, M.; Lim, T.; Kim, T.; Kim, S.; Suh, D. et al. (2017): Effectiveness of an application-based neck exercise as a pain management tool for office workers with chronic neck pain and functional disability: A pilot randomized trial. In: European Journal of Integrative Medicine 12, S. 87–92. DOI: 10.1016/j.eujim.2017.04.012.

Lee, M.; Lee, S. H.; Kim, T.; Yoo, H.-J.; Kim, S. H.; Suh, D.-W. et al. (2017): Feasibility of a Smartphone-Based Exercise Program for Office Workers With Neck Pain: An Individualized Approach Using a Self-Classification Algorithm. In: Archives of physical medicine and rehabilitation 98 (1), S. 80–87. DOI: 10.1016/j.apmr.2016.09.002.

Priebe, J. A.; Haas, K. K.; Sanchez, L.F.M.; Schoefmann, K.; Utpadel-Fischler, D. A.; Stockert, P. et al. (2020): Digital treatment of back pain versus standard of care: The cluster-randomized controlled trial, rise-up. In: Journal of pain research 13, S. 1823–1838.

Toelle, T. R.; Utpadel-Fischler, D. A.; Haas, K.-K.; Priebe, J. A. (2019): App-based multidisciplinary back pain treatment versus combined physiotherapy plus online education: a randomized controlled trial. In: npj Digital Medicine 2 (1). DOI: 10.1038/s41746-019-0109-x.

Yang, J.; Wei, Q.; Ge, Y.; Meng, L.; Zhao, M. (2019): Smartphone-Based Remote Self-Management of Chronic Low Back Pain: A Preliminary Study. In: Journal of Healthcare Engineering 2019. DOI: 10.1155/2019/4632946.

Zheng, Fuming; Liu, Shufeng; Zhang, Shanshan; Yu, Qiuhua; Lo, Wai Leung Ambrose; Li, Tingni; Wang, Chu Huai (2022): Does m-health-based exercise (guidance plus education) improve efficacy in patients with chronic low-back pain? A preliminary report on the intervention's significance. In: Trials 23 (1), S. 190. DOI: 10.1186/s13063-022-06116-z.

Literatur zu Programmfunktionen von tiNa-start


Garaud, Thomas; Gervais, Christine; Szekely, Barbara; Michel-Cherqui, Mireille; Dreyfus, Jean-François; Fischler, Marc (2018): Randomized study of the impact of a therapeutic education program on patients suffering from chronic low-back pain who are treated with transcutaneous electrical nerve stimulation. In: Medicine 97 (52), e13782. DOI: 10.1097/MD.0000000000013782.

Donevant, Sara Belle; Estrada, Robin Dawson; Culley, Joan Marie; Habing, Brian; Adams, Swann Arp (2018): Exploring app features with outcomes in mHealth studies involving chronic respiratory diseases, diabetes, and hypertension: a targeted exploration of the literature. In: Journal of the American Medical Informatics Association : JAMIA 25 (10), S. 1407–1418. DOI: 10.1093/jamia/ocy104.

Mental imagery/Positive psychology

Renner, Fritz; Murphy, Fionnuala C.; Ji, Julie L.; Manly, Tom; Holmes, Emily A. (2019): Mental imagery as a "motivational amplifier" to promote activities. In: Behaviour Research and Therapy 114, S. 51–59. DOI: 10.1016/j.brat.2019.02.002.

Velikova, Svetla; Sjaaheim, Haldor; Nordtug, Bente (2016): Can the Psycho-Emotional State be Optimized by Regular Use of Positive Imagery?, Psychological and Electroencephalographic Study of Self-Guided Training. In: Front. Hum. Neurosci. 10, S. 664. DOI: 10.3389/fnhum.2016.00664.

Müller, Rachel; Segerer, Wolfgang; Ronca, Elias; Gemperli, Armin; Stirnimann, Daniel; Scheel-Sailer, Anke; Jensen, Mark P. (2022): Inducing positive emotions to reduce chronic pain: a randomized controlled trial of positive psychology exercises. In: Disability and rehabilitation 44 (12), S. 2691–2704. DOI: 10.1080/09638288.2020.1850888.

Mindful meditation/Music

Ball, Elizabeth F.; Nur Shafina Muhammad Sharizan, Emira; Franklin, Genny; Rogozińska, Ewelina (2017): Does mindfulness meditation improve chronic pain? A systematic review. In: Current opinion in obstetrics & gynecology 29 (6), S. 359–366. DOI: 10.1097/GCO.0000000000000417.

Majeed, Muhammad Hassan; Ali, Ali Ahsan; Sudak, Donna M. (2018): Mindfulness-based interventions for chronic pain: Evidence and applications. In: Asian Journal of Psychiatry 32, S. 79–83. DOI: 10.1016/j.ajp.2017.11.025.

Watson, N.; Demetriou, G.; Cole, D.; Hassenkamp, A.-M.; Thomson, D. (2020): The effects of mindfulness training on persistent or intermittent sub-acute pain: using the Headspace® application. In: European Journal of Physiotherapy 22 (5), S. 253–261.

Lee, Jin Hyung (2016): The Effects of Music on Pain: A Meta-Analysis. In: Journal of music therapy 53 (4), S. 430–477. DOI: 10.1093/jmt/thw012.

Sakamoto, J. T.; Burrell, H. A.; Eucker, S. A. (2016): Are non-pharmacologic pain interventions effective at reducing pain in adult patients visiting the emergency department? In: Annals of Emergency Medicine 68 (4), S90.